BLUE
TKtomkindlon.bsky.social

New from Canada: Exploring the role of galectin-9 and artemin as biomarkers in #longCOVID#ChronicFatigueSyndromewww.frontiersin.org/journals/imm...#PASC#COVIDBrain#MEcfs#CFS

This study aimed to assess plasma galectin-9 (Gal-9) and artemin (ARTN)
 concentrations as potential biomarkers to differentiate individuals with Long
 COVID (LC) patients with myalgic encephalomyelitis/chronic fatigue syndrome
 (ME/CFS) from SARS-CoV-2 recovered (R) and healthy controls (HCs). Receiver
 operating characteristic (ROC) curve analysis determined a cut-off value of
 plasma Gal-9 and ARTN to differentiate LC patients from the R group and HCs
 in two independent cohorts. Positive correlations were observed between
 elevated plasma Gal-9 levels and inflammatory markers (e.g. SAA and IP-10), as
 well as sCD14 and I-FABP in LC patients. Gal-9 also exhibited a positive
 correlation with cognitive failure scores, suggesting its potential role in
 cognitive impairment in LC patients with ME/CFS. This study highlights plasma
 Gal-9 and/or ARTN as sensitive screening biomarkers for discriminating LC
 patients from controls. Notably, the elevation of LPS-binding protein in LC
 pati
0
Uundinium.bsky.social

S.o. Covidbrain befeuert das ganze noch. Das zu leugnen ist brandgefährlich.

1
TKtomkindlon.bsky.social

4/ "(Contd) The evidence presented indicates that COVID-19 and ADRD pathologies share common impacts on synaptic and neurovascular dysfunctions involving astrocyte reactivity and neuroinflammation." #LongCovid#PwLC#postcovid#postcovid19#LC#PostCovidSyndrome#longhaulers#PASC#COVIDBrain

0
TKtomkindlon.bsky.social

2/ "Our results suggest that in older adults with post-COVID syndrome, there is a pronounced shift from more global to local neural processing, potentially contributing to accelerated neural aging in this condition" #LongCovid#PwLC#PostCovidSyndrome#LC#PASC#postcovid#CovidBrain

0