Congratulations to Alexis Simon on the publication of "The contribution of gene flow, selection, and genetic drift to five thousand years of human allele frequency change" www.pnas.org/doi/10.1073/...

Always wondered how the immune system knows whom to fight? #PhD#MHC#TCRwww.uni-hamburg.de/en/stellenan...

my hopes for gen z taking over the academic process is that it will be matched for harshness, but at least more efficient

In new study led by Caleb Carr & Kate Crawford, we measure how all mutation to Lassa virus glycoprotein complex (GPC) affect cell entry & antibody escape   Results show how prospective assessment of effects of mutations can inform design of countermeasures www.biorxiv.org/content/10.1...

Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus gly...

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Announcing the call for fully funded 2 year postdoc positions for Clinician Scientists @dkfz.bsky.socialwww.dkfz.de/en/clinician...

'20 days after being infected with C. rodentium, only half of (C3 KO mice) survived. By contrast, all animals with normal C3 levels survived. 12 days after infection, mice lacking C3 had lost, on average, more than 20% of their body weight, whereas those with normal C3 levels lost no weight.'

Surprise find: a blood-based immune system is discovered in the gut

Immune guardians called complement proteins are manufactured by gut cells and help to protect against pathogens. Immune guardians called complement proteins are manufactured by gut cells and help to p...

A great #immunology account to follow at the bad place is now here as well 👇

Iimmunoboys.bsky.socialFeb 5, 2024 6:46pm

Highlighting the duality between (autoimmunity-related) age-associated B cells and Germinal Center B cells, Dai et al identified ZEB2 as a critical TF for the development of age-associated B cells. ZEB2 represses Mef2b (a GC B cell TF) and induces typical ABC phenotype 1/2

T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery

TCcyrilpedia.bsky.socialFeb 7, 2024 10:38am

'Here, we present (...) a system to rapidly deconvolute CD4 and CD8 TCRs and targets physiologically processed and presented by an individual’s unmanipulated, complete human leukocyte antigen (HLA) haplotype' www.science.org/doi/10.1126/...

PhD opportunity in my group at UiO on adaptation to shifting temperatures in house sparrows. Looking for candidates interested in combining evolutionary genomics and ecological approaches! Please share! www.jobbnorge.no/en/available...

Today is the deadline for: 📄 Abstract submission 🐦 Early bird registration (with a reduced fee) 🪙 Application for travel grants Register now for the 75th Mosbacher Kolloquium at mosbacher-kolloquium.org