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Libusha Kelly
@microbegrrl.bsky.social
Microbiome, drugs, phages, ecology, the Bronx
118 followers86 following14 posts
Reposted by Libusha Kelly
EHpipethero.bsky.social

Delighted to share work by Kristie Yu, Celine Son, & co showing that selective fructan metabolism by the gut microbiome can contribute to host associative learning of dietary preference, even when it comes to choosing between diets with the same perceptual salience (and macronutrient composition!)

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Reposted by Libusha Kelly
ALasherleeks.bsky.social
Reposted by Libusha Kelly
JWjoshuasweitz.bsky.social

Delighted to announce a call for applications for the PSL-QLife Summer School on 'Quantitative Phage-Bacteria Dynamics Across Scales', to be held in Paris, July 8-12, 2024.  Application deadline April 8, 2024: www.edu.bio.ens.psl.eu/spip.php?art...

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LKmicrobegrrl.bsky.social

The department of Cell Biology at Einstein is hiring! Cell, molecular, computational biology focus, all levels. www.nature.com/naturecareer...

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Reposted by Libusha Kelly
HEhollyenglish.bsky.social

This is so cool! Generate your Google Scholar word cloud here: shiny.rcg.sfu.ca/u/rdmorin/sc... 🧪👩‍⚕️

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Reposted by Libusha Kelly
MDlizscurious.bsky.social

New collaborative work from our lab on the transmission of AMR in a community context. www.biorxiv.org/content/10.1... We find that Gram positive bacteria, particularly enterocci, increase the conjugation efficiency of uropathogenic E.coli.

Community context influences the conjugation efficiency of E. coli
Community context influences the conjugation efficiency of E. coli

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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Reposted by Libusha Kelly
ERepcrocha.bsky.social

New from the lab. We were stuck studying plasmid mobility because we ignored most origins of transfer by conjugation. Using the occurrences of known oriT, we developed a method to find novel unrelated families. Works well. We now cover most conjugative plasmids of E coli, K pneumo & A baumannii.

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Reposted by Libusha Kelly
Vviroid.bsky.social

There's a ~1000nt sub-viral RNA that shows up on every continent, and in humans, and it seems to have gone unnoticed! It has no sequence similarity to any database and codes for a wacky protein Super happy to finally share my thesis work on "Obelisks" tinyurl.com/yc54fzj9#MicroSky#microbiomesky

A multi-panel diagram of features about "Obelisks". Top half, a) schematics of Obelisk-alpha, a 1164 nt long, apparent;y circular, predicted to be rod-shaped RNA that codes for two proteins, Oblin-1 and Oblin-2 where Oblin-1 is self-complementary. Obelisks bare no sequence similarity to any annotated genetic sequence. The predicted secondary structure is depicted as "Jupiter" plots (circular diagrams where chords represent predicted base pairs), and as skeleton diagrams (where parallel lines represent predicted base pairs). Bottom left, b) a schematic of the world map, with nations coloured in shades of red representing the number of datasets (from a subset database) that contain Obelisks (redder = more datasets), nations from all 7 continents are shaded. Bottom right, c) a predicted tertiary structure for Oblin-1, that appears to be a novel fold, represented as in cartoon format and as a topological diagram (right).
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Reposted by Libusha Kelly
MKmkrupovic.bsky.social

Have a look at our paper on a new group of pleomorphic viruses infecting marine hyperthermophilic #archaeadoi.org/10.1093/isme...

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Reposted by Libusha Kelly
LKmicrobegrrl.bsky.social

and the recent discoveries of novel viriod-like 'obelisks' @viroid.bsky.social, new programmable recombinase systems from Patrick Hsu + others, and minimalist phage satellites Frédérique Le Roux, there's paradigm-shifting work going on. (9/9 fini!)

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LK
Libusha Kelly
@microbegrrl.bsky.social
Microbiome, drugs, phages, ecology, the Bronx
118 followers86 following14 posts