SM
Stefan Marciniak
@profmarciniak.bsky.social
Professor of Respiratory Science University of Cambridge. Lung doctor. Fellow St Catharine’s College. Cell biology. Pleural medicine. Rare disease. Genetics.
1k followers577 following377 posts
OXBRYTA (voxelotor) withdrawn FDA 2019 accelerated approval 2019 EC marketing authorisation 2022 Designed to inhibit sickle hemoglobin polymerisation, but ongoing monitoring indicates benefit no longer outweighs risk in the sickle cell patient population www.pfizer.com/news/press-r...
Disappointing that a medication for such an important unmet need is withdrawn, but this highlights the importance of post market surveillance of new (or any) drug
SM
Stefan Marciniak
@profmarciniak.bsky.social
Professor of Respiratory Science University of Cambridge. Lung doctor. Fellow St Catharine’s College. Cell biology. Pleural medicine. Rare disease. Genetics.
1k followers577 following377 posts