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Tom Kindlon
@tomkindlon.bsky.social
95% of posts on #MyalgicEncephalomyelitis, #LongCovid or #chronicillness. With ME/CFS 35 years, severe ME 30 years. @IrishMECFSAssoc trustee 27 years 26 publications in peer-reviewed journals Social media: me-pedia.org/wiki/Tom_Kindlon
1.2k followers68 following3.2k posts
TKtomkindlon.bsky.social

New from Canada: Exploring the role of galectin-9 and artemin as biomarkers in #longCOVID#ChronicFatigueSyndromewww.frontiersin.org/journals/imm...#PASC#COVIDBrain#MEcfs#CFS

This study aimed to assess plasma galectin-9 (Gal-9) and artemin (ARTN) concentrations as potential biomarkers to differentiate individuals with Long COVID (LC) patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) from SARS-CoV-2 recovered (R) and healthy controls (HCs). Receiver operating characteristic (ROC) curve analysis determined a cut-off value of plasma Gal-9 and ARTN to differentiate LC patients from the R group and HCs in two independent cohorts. Positive correlations were observed between elevated plasma Gal-9 levels and inflammatory markers (e.g. SAA and IP-10), as well as sCD14 and I-FABP in LC patients. Gal-9 also exhibited a positive correlation with cognitive failure scores, suggesting its potential role in cognitive impairment in LC patients with ME/CFS. This study highlights plasma Gal-9 and/or ARTN as sensitive screening biomarkers for discriminating LC patients from controls. Notably, the elevation of LPS-binding protein in LC pati
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TK
Tom Kindlon
@tomkindlon.bsky.social
95% of posts on #MyalgicEncephalomyelitis, #LongCovid or #chronicillness. With ME/CFS 35 years, severe ME 30 years. @IrishMECFSAssoc trustee 27 years 26 publications in peer-reviewed journals Social media: me-pedia.org/wiki/Tom_Kindlon
1.2k followers68 following3.2k posts
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