We combined this with biochemical isolation and characterisation of EVs, electrophysiology recordings and mathematical modelling to arrive at an ‘on-demand release’ model 3/5

We hope that this will provide a framework to better understand endocannabinoid signalling. Check out the manuscript for the full story: www.biorxiv.org/content/10.1... 4/5

The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles

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