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Werte des Tau-Proteins, das sich bei Alzheimer ungewƶhnlich stark verformt. Dies deutet darauf hin, dass #COVID19onlinelibrary.wiley.com/doi/10.1111/...#Alzheimers#CleanAir#MaskUp#Coronavirus#TeamVorsicht

Prolonged upregulation of glia activation and inflammatory factors expression in the hippocampus post-acute COVID-19. (a, b) Representative immunofluorescent images (a) and 3D-reconstruacted morphology (b) of Iba1-stained microglia. (cā€“e) The number of microglia did not change (c), but soma volume significantly increased (d) and branches complexity decreased (e) in acute and post-acute COVID-19. Nā€‰=ā€‰6ā€“7 patients or 174ā€“382 cells in each group, ***pā€‰<ā€‰0.001, one-way (c, d) and repeated measures (e) ANOVA followed by Tukey's multiple comparisons tests. (f, g) Representative immunohistochemical images (f) and Sholl analysis diagram (g) of GFAP-stained astrocytes. (hā€“j) The number of astrocytes did not change (h), but both soma volume (i) and processes complexity (j) significantly increased in acute and post-acute COVID-19. Nā€‰=ā€‰6ā€“7 patients or 108ā€“194 cells in each group, ***pā€‰<ā€‰0.001, one-way ANOVA followed by Tukey's multiple comparisons tests. (k) mRNA levels of inflammatory factors ā€¦
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Eesiode.bsky.social

šŸ“ƒScientific paper: Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology āž”ļø Continued on ES/IODE

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TCcyrilpedia.bsky.social

'In vertebrates, some astrocytes may even be involved in the presentation of antigens to infiltrating T cells. This places them as key initiators of the earliest response to inflammation, without the need for a myeloid cell intermediary.' #Immunology#Immunoskywww.cell.com/trends/immun...

Emerging roles of astrocytes as immune effectors in the central nervous system
Emerging roles of astrocytes as immune effectors in the central nervous system

The astrocyte, a major glial cell type in the central nervous system (CNS), is widely regarded as a functionally diverse mediator of homeostasis. During development and throughout adulthood, astrocyte...

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Eesiode.bsky.social

šŸ“ƒScientific paper: Astrocytes Transplanted during Early Postnatal Development Integrate, Mature, and Survive Long Term in Mouse Cortex āž”ļø Continued on ES/IODE

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Eesiode.bsky.social

šŸ“ƒScientific paper: Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology āž”ļø Continued on ES/IODE

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