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CBcbammermd.bsky.social

Small update: In the mentioned case, significantly elevated IL-8 and markedly reduced IL-10 were observed; the remaining cytokine profile was not very informative, and the lymphocyte subpopulations were unremarkable except for usually low NK cells. The GPCR autoantibodies were again highly positive.

CBcbammermd.bsky.social

I write here irregularly about my experiences in my clinic for post-infectious and other multisystem diseases. #PAIS #MECFS #PostCOVID #Postvac Today: What about RSV? 1/5

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TIinteractivefly.bsky.social

Ono, M., Matsumura, T., Sung, E. J., Koyama, T., Ochiai, M., Shears, S., Hayakawa, Y. (2024). Drosophila cytokine GBP2 exerts immune responses and regulates GBP1 expression through GPCR receptor Mthl10. Insect biochemistry and molecular biology. 167:104086 www.sciencedirect.com/science/arti...

Drosophila cytokine GBP2 exerts immune responses and regulates GBP1 expression through GPCR receptor Mthl10
Drosophila cytokine GBP2 exerts immune responses and regulates GBP1 expression through GPCR receptor Mthl10

Growth-blocking peptide (GBP), an insect cytokine, was first found in armyworm Mythimna separata. A functional analogue of GBP, stress-responsive pept…

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TCcyrilpedia.bsky.social

Absolutely, this was in 2005, with a KO for a GPCR that was made by another group. They said it had a lupus-like autoimmune syndrome, which was not their primary concern. The autoimmunity seemed to really depend on the residual 129 genes (lk all of immunology at the time, we were backcrossing to b6)

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