James Martin write about how pregnancy enhances anti flu immunity independent of type 1 IFN, but relies on IL-17 GDTs in the nasal mucosa. [11/n] www.science.org/doi/full/10....
Enhanced antimicrobial immunity in the upper airways protects against IAV infection during pregnancy.
Trichomonas vaginalis extracellular vesicles suppress IFNϵ-mediated protection against host cell cytolysis www.biorxiv.org/content/10.1101/2024.10.02.616276v1
Trichomonas vaginalis is a commonly acquired sexually transmitted infection (STI) often found in sym
Trichomonas vaginalis extracellular vesicles suppress IFNϵ-mediated protection against host cell cytolysis www.biorxiv.org/content/10.1101/2024.10.02.616276v1
Trichomonas vaginalis is a commonly acquired sexually transmitted infection (STI) often found in sym
Immune response in vaccinated healthcare workers with frequent COVID-19 infections is characterised by blunted IFNγ and IL-2 responses to SARS-CoV-2 variants What happens if you are frequently infected with SARS-CoV-2? www.sciencedirect.co... 1/8
Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. Despite widespread vaccination, some HCWs develop frequent symptomatic infect…
Here, the authors show that lung macrophages, upon SARS-CoV-2 infection, increase the activity of type I interferon (IFN-I)-related transcription factors and epigenetic poising of antiviral genes, which improves secondary antiviral responses. such as against influenza virus. 4/7
#heycohost it's me It's us I wasted all the good writey spoons being poetic Follow me ifn u wants
CD69, CD103, CD49a, and CXCR6, and exerted immediate effector functions. In particular, nasal-resident CD49a+CD8+ memory T cells exhibited enhanced IFN-γ production, among all vaccinees regardless of infection history." 5/6
SARS-CoV-2 spike-specific nasal-resident CD49a+CD8+ memory T cells exert immediate effector functions with enhanced IFN-γ production SARS-CoV-2 vaccination also results in effective local immunity, and infection does not reduce this. www.nature.com/artic... 1/6
Nature Communications - For infections that affect peripheral tissues it is better to promote immune responses in these tissues. Here the authors characterise nasal mucosal SARS-CoV-2-specific T...
#MedSky🧪#iDSky#ImmunoSky#COVID#SARSCoV2www.sciencedirect.com/science/arti...
Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. Despite widespread vaccination, some HCWs develop frequent symptomatic infect…