A direct computational assessment of vinculin-actin unbinding kinetics reveals catch bonding behavior www.biorxiv.org/content/10.1101/2024.10.10.617580v1
Vinculin forms a catch bond with the cytoskeletal polymer actin, displaying an increased bond lifeti
A direct computational assessment of vinculin-actin unbinding kinetics reveals catch bonding behavior www.biorxiv.org/content/10.1101/2024.10.10.617580v1
Vinculin forms a catch bond with the cytoskeletal polymer actin, displaying an increased bond lifeti
Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics www.biorxiv.org/content/10.1101/2024.10.11.617960v1
Fumarate-adding enzymes (FAE) are a subset of the glycyl radical enzyme superfamily involved in anae
Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics www.biorxiv.org/content/10.1101/2024.10.11.617960v1
Fumarate-adding enzymes (FAE) are a subset of the glycyl radical enzyme superfamily involved in anae
co-ordinating responses from our vagus nerve feedback loop is something i've been doing in-deep with my Age Concern counselor, nothing to do with martial arts, just keeping sōf more or less sane it has surprising connections to the kinetics of taichi
Data-driven Bayesian estimation of Monod kinetics https://arxiv.org/abs/2402.04727 In this paper, we consider the well known problem of non-linear identification of the rates of the reactions involved in cells with Monod functions. In bioprocesses, generating data is very expensive and long and s 📈🤖
What I did know about were mechanisms, kinetics, isotope effects, etc., so I actually knew the most at group meetings but the least at the bench. By the end of the first year, I had the hang of it, and things went great. Gerlt liked me, which was very fortunate, of course!
First, as an undergrad I hated kinetics. It was all boring equations and seemed unrelated to reaction mechanisms. (Bad teaching? Bad student?) Anyway, I discovered that once you care about the reaction, kinetics was fascinating, and I was good at doing consistent experiments and detective work.
Cargo adaptor identity controls the mechanism and kinetics of dynein activation www.biorxiv.org/content/10.1101/2024.10.09.617440v1
Cytoplasmic dynein-1 (dynein), the primary retrograde motor in most eukaryotes, supports the movemen
Cargo adaptor identity controls the mechanism and kinetics of dynein activation www.biorxiv.org/content/10.1101/2024.10.09.617440v1
Cytoplasmic dynein-1 (dynein), the primary retrograde motor in most eukaryotes, supports the movemen