1) They are the one known causal genetic effect on alcohol use. 2) They were discovered in the 90s via linkage (ie not GWAS). 3) They account for essentially 0 variance among drinkers in the US, eg in S4S.

In particular, we can't pre-identify genetic traits that actually predict specific (behavioral) phenotypes in the future. At least for alcohol, in a real-world applied situation like S4S, the "predisposition" accounted for like .005 of the variance, and that is without family level controls. /2

Did you try the s4s dx11 batch fix on the khippie files? That should fix it so you can still move to dx11.

Last Starlight Children's Foundation stream for the year via @tiltify.bsky.socialtwitch.tv/johan_singa#Twitch#S4S#DeliveringHappiness

🔴 LIVE NOW 🔴 Enzo le Croco returns for the last Just Dance stream of the month while also fundraising for Starlight Children's Foundation via @tiltify.bsky.socialtwitch.tv/johan_singa#Twitch#S4S

Nomes BR pra aplicativo é uó, e dificilmente pega, mas se pudesse usar nome inglês seria legal "shine for skin" e a abreviatura seria "S4S".

🔴 LIVE NOW 🔴 Starting my morning with Just Dance! How do you start your morning? We're also fundraising for Starlight Children's Foundation via @tiltify.bsky.social#DeliverHappinesstwitch.tv/johan_singa#Twitch#S4S

Most scars, skin details and make up can be easily converted to children with the help of sims4studio. If you find one you like for adults, open the file on s4s and add "children" to the categories in that piece, apply to all swatches and save. I've done this with skin details and works like a charm

Yes, they're default replacements created through S4S. I've seen a few default replacements that aren't tagged as modded, so I thought it might be possible to so something like that with default replacements specifically

🔴 LIVE NOW 🔴 We’re reacting to the PlayStation State of Play, then finally giving Terry Bogard a go in Street Fighter 6! We're also still fundraising for Starlight Children's Foundation via @tiltify.bsky.social#DeliverHappinesstwitch.tv/johan_singa#Twitch#S4S