Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells. www.biorxiv.org/content/10.1101/2024.09.12.612728v1
The cyclin D1-Cyclin-Dependent Kinases 4 and 6 (CDK4/6) complex is crucial for the development of me
Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells. www.biorxiv.org/content/10.1101/2024.09.12.612728v1
The cyclin D1-Cyclin-Dependent Kinases 4 and 6 (CDK4/6) complex is crucial for the development of me
Calcium (Ca2+) fluxes at Mitochondria-ER Contact Sites (MERCS) are a new target of senolysis in Therapy-Induced Senescence (TIS). www.biorxiv.org/content/10.1101/2024.03.31.587471v1
This study investigates the state of calcium (Ca2+) flux and Mitochondria-ER contact sites (MERCS) o
Calcium (Ca2+) fluxes at Mitochondria-ER Contact Sites (MERCS) are a new target of senolysis in Therapy-Induced Senescence (TIS). www.biorxiv.org/content/10.1101/2024.03.31.587471v1
This study investigates the state of calcium (Ca2+) flux and Mitochondria-ER contact sites (MERCS) o
Therapeutic opportunities for #Senolysis#Atherosclerosis#MyocardialInfarction#HeartFailure#CardioOncology#PulmonaryHypertension#FEBSJfebs.onlinelibrary.wiley.com/doi/full/10....
USP7 Inhibition Promotes Mesenchymal Stem cell-Macrophage Crosstalk in Age-related Osteoporosis via Efferocytosis and Senolysis www.biorxiv.org/content/10.1101/2023.11.15.567232v1
The interaction between bone mesenchymal stem cells (BMSCs) and macrophages in osteoporosis has gain
USP7 Inhibition Promotes Mesenchymal Stem cell-Macrophage Crosstalk in Age-related Osteoporosis via Efferocytosis and Senolysis www.biorxiv.org/content/10.1101/2023.11.15.567232v1
The interaction between bone mesenchymal stem cells (BMSCs) and macrophages in osteoporosis has gain
Genetic (p16-3MR) vs Pharmacological (ABT263) #Senolysis#CardiovascResacademic.oup.com/cardiovascre...
In my experience, joint pain responds the fastest within one to two days after the senolysis treatment. However, senolysis affects all organs, e.g. heart, vessels, brain … and it not only has anti-inflammatory effects but also rejuvenating ones.