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MVmarcveld.bsky.social

Here, the authors show that lung macrophages, upon SARS-CoV-2 infection, increase the activity of type I interferon (IFN-I)-related transcription factors and epigenetic poising of antiviral genes, which improves secondary antiviral responses. such as against influenza virus. 4/7

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MVmarcveld.bsky.social

This "innate memory" can take two main shapes. It is a short-lived feedback mechanism largely thought to prevent an overactive response and damage to self. But it can also take epigenetic changes, increasing a "recall" response, e.g., quicker expression of antiviral factors. 3/7

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Genetic and neuro-epigenetic effects of divergent artificial selection for feather pecking behaviour in chickens #neurodegeneration https://www.researchsquare.com/article/rs-4998568/latest

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TFtopherflorence.bsky.social

if you take metal gear solid 2 at face value (without the larger canon) everything revolving liquid snake's arm technically has the same framework of epigenetic memory as when urkel turns into bruce lee

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DNthekirz.bsky.social

Being a direct descendant, I'm curious and a little anxious about the epigenetic effects of the Holocaust. My grandparents (survivors) lived to be MUCH older (30-40 yrs) than their children.

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DSduanemoody.bsky.social

My daughter the bio scientist reminds me that "immune response" like "cancer" is a catch-all term for multiple phenomena which likely does not have some epigenetic switch to turn off and my own guess is my father's family line evolved this as a response to something like plague centuries ago.

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