Weekly recap: A new eQTL Nextflow workflow, spatial transcriptomics / scRNA-seq, guide assignment in CRISPR screens, on-/off-target analysis after CRISPR editing experiments, digital microbes, paleogenomics, ... blog.stephenturner.us/p/weekly-rec... 🧬🖥️

Weekly Recap (Sep 2024, part 5)

A new eQTL Nextflow workflow, spatial transcriptomics / scRNA-seq, guide assignment in CRISPR screens, on-/off-target analysis after CRISPR editing experiments, digital microbes, paleogenomics, ...

Susanne Renner, “Paleogenomics reveals angiosperm karyotype evolution during their early history and shows that Amborella belongs in the Nymphaeales.” Reviewed Amborella phylogenetic placement (low certainty?) vs unpublished study using ancestral karyotype methods of Salse #ibc2024#Botany 🌾🧪🌱🌍🌿🍄🌻🔬

Here's a "behind the scenes" account of the latest Late Neolithic plague study by the first-author: www.nature.com/articles/d41...#histmed#paleogenomics 🧪

#paleontology#palaeontology#paleosky#mammoths#paleogenomics#palaeogenomics#AncientDNA

More details, including some about the technique used to preserve the fruit 250 years ago. An Agricultural Research Service geneticist working with archeologists on the project - cool! Not quite paleogenomics, but fun. #Botanywww.npr.org/2024/06/20/n...

Centuries-old cherries were found at George Washington's home. What can they tell us?

Archaeologists unearthed 35 bottles of cherries from the cellar of George Washington's Mount Vernon. The 250-year-old fruits, many still intact, can shed new light on those who lived and worked there.

this paper got mentioned casually offhand in a podcast I was listening to where they had a ton of academic historians doing a roundtable on paleogenomics’ effects on the field, and I was yelling at my phone like “excuse me WHAT”

Oooh, another "cast of 1000s" #Paleogenomicswww.nature.com/articles/s41.... "Reproductive control emerged following a severe domestication bottleneck starting no earlier than ~2,700 BCE, [which] ultimately resulted in the replacement of nearly every local horse lineage."

Already had very interesting talks in the #Paleogenomics#dysmorphology#ESHG2024#HumanGenetics#juhumgen#ESHG

💕 Happy Valentine’s Day! Is your one true love ancient pathogens? 🧬 Abstracts for #SMBE2024smbe2024registration.org/abstracts 🦠 We would love to have you join us at “Unveiling the evolutionary history of pathogens through paleogenomics”! 🏝️ See you in Puerto Vallarta in July!