Tropical Storm Milton has taken shape in the western Gulf of Mexico. It is expected to run right over Tampa on Wednesday as a Category 3 hurricane.
INSL6:p (insulin like 6) is a little overweight for a proprotein (21-213), containing an A-chain (173-198), B-chain (21-53) and C-peptide (55-168) for the named hormone. Peptides from all three named peptide domains are observable in spermatozoa. Function: your guess is as good as anyone's.
No idea what it might be up to in milk, although what it is doing in CSF, plasma or urine isn't exactly clear, either.
For the mouse model crowd, it would appear that mice may be using (or at least making) INSL5:p in a similar way to humans, so your favourite platform may turn out to be useful in this case.
INSL5:p (insulin like 5) is an insulin-sized proprotein (23-135) that contains an A-chain (115-135), B-chain (23-46) & C peptide (49-114) that is fabricated and secreted by the large intestine, although a function associated with this little guy is still for […] [Original post on mastodon.social]
IGFBP1:p, insulin like growth factor binding protein 1 (Homo sapiens) Small subunit; CTMs: ∅; PTMs: 0×K+acetyl; 0×K+succinyl; 0×K+GGyl; 0×K+SUMOyl; 5×S, 2×T, 0×Y+phosphoryl; SAVS: I253M (36%); mature form: (25,26,28-259, 4 exons) [2,009×, 23 kTa]. θ(max) = […] [Original post on mastodon.social]
INSL4:p (insulin like 4) is a suitably small proprotein (25-139) that contains the sequence for an A-chain (115-139), B-chain (26-58) & a C-peptide (59-114). It is secreted by endocrine cells in the placenta, although why this occurs is still pretty mysterious.
