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Addgene
@addgene.bsky.social
Sharing speeds science! Addgene helps scientists around the world find and share research materials - plasmids, viral preps, antibodies, data, and more.
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New pooled libaries available from the Gonatopoulos-Pournatzis lab! These CHyMErA libraries can be used by scientists to determine important exons and study mechanisms that control cellular fitness and gene expression. www.addgene.org/pool...

A diagram depicts a cell expressing both Cas12a and Cas9 nucleases. Lines indicate that we are looking at a magnified view of the nucleus. The schematic structure of the hgRNA is shown, consisting of a U6 promoter, Cas9 guide (Cas9 spacer and tracrRNA), and Cas12a guide (direct repeat and Cas12a spacer). An arrow points from the hgRNA to a diagram in which Cas9 hgRNA or Cas12a hgRNA complexes are bound to target DNA. Scissors show cut sites within exons or flanking an exon.
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Addgene
@addgene.bsky.social
Sharing speeds science! Addgene helps scientists around the world find and share research materials - plasmids, viral preps, antibodies, data, and more.
1k followers210 following649 posts