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Albert Vilella, PhD.
@albertvilella.bsky.social
Bioinformatics Scientist / Next Generation Sequencing / Single Cell and spatial biology / Next Generation Proteomics / Liquid Biopsy/ SynBio / Compute Acceleration // albertvilella.substack.com
2.8k followers6k following483 posts
AValbertvilella.bsky.social

Bard 2024-01-25: BCSQ=@1887: This refers to a quality score for the variant call stored at another location in the VCF file (at line 1887). This is mostly correct.

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AValbertvilella.bsky.social

.... it continues: This score is likely calculated using the Bayesian Confidence Score (BCS) method, which takes into account various factors like mapping quality, variant frequency, and strand bias. I don't think this is correct, I think BCS is unrelated.

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Albert Vilella, PhD.
@albertvilella.bsky.social
Bioinformatics Scientist / Next Generation Sequencing / Single Cell and spatial biology / Next Generation Proteomics / Liquid Biopsy/ SynBio / Compute Acceleration // albertvilella.substack.com
2.8k followers6k following483 posts