Excited to be part of this effort with @biotobi.bsky.social@meyerbritta.bsky.socialwww.biorxiv.org/content/10.1...

Complete sequencing of ape genomes

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

In this work, we show how valuable long read technology is for full characterization and annotation of MHC genes on fully phased diploid haplotypes.

In humans, the 30Mbish MHC region is the most gene dense region of the genome and associated with more diseases than any other genomic region. Its often hard however to study this region genomically due to complex evolutionary patterns of the MHC