Foot-and-mouth disease virus studies: Heat inactivation of virus-positive milk samples required higher temperature or longer incubation times (or both) than heat inactivation of virus spiked into milk because fat globules & casein micelles protect viruses in virus-positive milk.

We detected high virus titers in the respiratory organs (which suggests that infection may have occurred through the pharynx) and moderate virus titers in several other organs, findings consistent with the systemic infections typically caused by HPAI H5 viruses in mammals.