Optimization of methods for rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system www.biorxiv.org/content/10.1101/2024.09.27.615502v1
CRISPR/Cas9 has massively accelerated the generation of gene loss-of-function models in zebrafish. H
Direct and Indirect Regulation of SIX1+EYA Transcriptional Activity by PA2G4, MCRS1, and SOBP www.biorxiv.org/content/10.1101/2024.09.28.615612v1
Branchio-oto-renal (BOR) syndrome is an autosomal dominant condition characterized by variable crani
ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans www.biorxiv.org/content/10.1101/2024.09.29.615693v1
Signaling by the LET-60 Ras GTPase/MPK-1 Extracellular Regulated Kinase pathway specifies the vulva
Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration www.biorxiv.org/content/10.1101/2024.09.28.615596v1
Tissue regeneration relies on precise molecular mechanisms controlling cell fate transitions, with c
Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres www.biorxiv.org/content/10.1101/2024.09.28.614398v1
During pre-implantation mouse embryonic development, blastomeres undergo division and differentiatio
Zebrafish glial-vascular interactions progressively expand over the course of brain development www.biorxiv.org/content/10.1101/2024.09.27.615488v1
Glial-vascular interactions are critical for the formation and maintenance of brain blood vessels an
Homeodomain protein codes specify neuronal diversity in the first ganglion of the Drosophila visual system www.biorxiv.org/content/10.1101/2024.09.27.615552v1
Recent advances in single-cell transcriptional profiling have enabled us to map diverse neuron types
Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis www.biorxiv.org/content/10.1101/2024.09.25.612672v1
In the first postnatal month, the developing mouse intestine shifts from an immature to a mature int
Differential responses and recovery dynamics of HSPC populations following Plasmodium chabaudi infection. www.biorxiv.org/content/10.1101/2024.09.25.614952v1
Severe infections such as malaria are on the rise worldwide, driven by both climate change and incre
Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of Insm1, Ikzf2, and Triobp genes www.biorxiv.org/content/10.1101/2024.09.24.614849v1
The RFX family of transcription factors plays crucial roles in the regulation of ciliogenesis and or