CM
Chris Miller
@chrismiller.science
Associate Professor @ Washington University in St Louis. Cancer Genomics, Bioinformatics, Data Viz, Tumor Evolution, AML, Immunotherapy, Irreverent humor 🧬 🖥️
214 followers107 following185 posts
When you design a mRNA vector, you're usually including sequence that translates to the the mutated AA, plus a dozen or more AAs on either side. Seems like there still could be a fair amount of room to optimize codons within that vector for better stability and expression.
It seems like a great task for an AI model, and something that might lend itself to high-throughput screening
CM
Chris Miller
@chrismiller.science
Associate Professor @ Washington University in St Louis. Cancer Genomics, Bioinformatics, Data Viz, Tumor Evolution, AML, Immunotherapy, Irreverent humor 🧬 🖥️
214 followers107 following185 posts