Our paper describing a new sequencing-based neutralization assay for influenza virus is now published in Journal of Virology: journals.asm.org/doi/10.1128/... This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
Here is analysis of HA mutations in H5 influenza case in Missouri resident without known contact w animals or raw milk. TLDR: there is one HA mutation that strongly affects antigenicity, and another that merits some further study.
(More precisely, if *started* within the first five days post-onset)
It’s not clear to me that the antiviral only helps if taken within the first five days. I understand that was the inclusion criterion in the original trial, but I am curious if there are data suggesting it is not helpful past this window.
🚨 FYI @ R Users 🚨 Serious security vulnerability in R "up to and not including 4.4.0, enabling a maliciously crafted RDS (R Data Serialization) formatted file or R package to run arbitrary code on an end user’s system when interacted with." 😱 nvd.nist.gov/vuln/detail/...
Breaking: A farmworker in Michigan has been diagnosed with bird flu, state officials announced on Wednesday, making it the second human case associated with the outbreak in cows. www.nytimes.com/2024/05/22/h...
The new case, in a Michigan farmworker, did not suggest that bird flu was widespread in people, health officials said, adding that the risk to the general public remained low.
Public health doesn't have the legal authority to march onto farms and make farmers comply. USDA does have the legal authority to go onto farms uninvited to test. It is not using it.
New tool announcement! Thanks to a lot of work from Jordan Ort (an awesome student in the lab), with help from @richardneher , Todd Davis, Tommy Lam, and Sam Shepard, the H5s are now on Nextclade! clades.nextstrain.org A thread below:
Principles for university governance of protests: 1) *actual* threats to the safety of other university members, which is not the same as "chants and posters that arguably evoke and approve of violence elsewhere in the world," can't be tolerated. 2) *actual* impairment of the safety of other 1/
SCOOP: Federal officials have shared little information on the bird flu outbreak in dairy cows and have said it is limited. But asymptomatic cows found in North Carolina have changed the situation.
Testing for H5N1 infection has been limited, and the outbreak was never confined. But asymptomatic cows in North Carolina may require a reassessment.