'Perhaps the hardest part of this problem is to shift our preconceptions. The size of the PKZILLAs, the researchers say, ‘expands our imagination on the capabilities of enzymes in the construction of complex molecules.’ www.chemistryworld.com/opinion/enor...

Enormous enzymes expand the limits of molecular biology

Identifying the PKZILLAs, used by algae to make toxins, stretched the capabilities of current analytical methods - and the limits of our preconceptions