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Dor Salomon
@drdorsalomon.bsky.social
Associate Professor at Tel Aviv University. Interested in bacterial toxins and secretion, antibacterial bio-treatments, Vibrio, syn bio, host-microbe interactions, T6SS, anti-phage defense, MGEs www.dorsalomonlab.sites.tau.ac.il/
191 followers61 following73 posts
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Our paper is out: We found a T6SS delivery domain, PIX, that mediates effector loading onto the system. PIX, which is restricted to Enterobacterales, revealed hundreds of polymorphic T6SS effectors. 🦠 In loving memory of our mentor, collaborator, and friend, Guido Sessa www.cell.com/cell-reports...

PIX is an N-terminal delivery domain that defines a class of polymorphic T6SS effectors in Enterobacterales
PIX is an N-terminal delivery domain that defines a class of polymorphic T6SS effectors in Enterobacterales

Carobbi et al. report a class of orphan polymorphic T6SS effectors in Enterobacterales. These effectors employ an N-terminal PIX domain that binds a VgrG protein to mediate secretion.

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DS
Dor Salomon
@drdorsalomon.bsky.social
Associate Professor at Tel Aviv University. Interested in bacterial toxins and secretion, antibacterial bio-treatments, Vibrio, syn bio, host-microbe interactions, T6SS, anti-phage defense, MGEs www.dorsalomonlab.sites.tau.ac.il/
191 followers61 following73 posts