TRβ activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPA nature.com/articles/s41... In conclusion, our observations support the idea that masking pathologic plasticity and facilitating endogenous differentiation potential of AT2 cells 1/2

TRβ activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPA - Nature Communications

Here, Xin Pan and colleagues found that activation of thyroid hormone receptor-β is necessary for alveolar epithelial cell differentiation during lung repair and regeneration, and confirmed a specific...

is an inspiring strategy to promote normal regeneration and anti-fibrosis, and TRβ activation is a highly promising strategy to fulfill this intractable task by orchestrating KLF2 and CEBPA. 2/2