GC
Graham Coop
@gcbias.bsky.social
Popgen @UCDavis @gcbias@ecoevo.social . Posts, grammar, & spelling are my views only. He/him. #OA popgen book github.com/cooplab/popgen-notes/releases
1.7k followers592 following366 posts
My lab read this paper www.biorxiv.org/content/10.1... for journal club, and had some thoughts on the strong claims made about the number of signals of selection found.
Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
The GLMM test that is applied in the paper, which gives the Z statistic and estimated selection coefficients, is looking for SNPs that show a consistent temporal allele frequency change. That is equivalent to Gene Environ correlation methods using time as the environment. 2/
GC
Graham Coop
@gcbias.bsky.social
Popgen @UCDavis @gcbias@ecoevo.social . Posts, grammar, & spelling are my views only. He/him. #OA popgen book github.com/cooplab/popgen-notes/releases
1.7k followers592 following366 posts