Experts from diverse fields gathered at #cshlsymp24genesdev.cshlp.org/content/curr...
NEW ISSUE ALERT!!! Featuring a collection of Outlooks inspired by the 88th CSHL Symposium on Brain-Body Physiology as well as new Research and Review Articles, online now at Genes & Development. #cshlsymp24genesdev.cshlp.org/content/curr...
In this study, Traynor et al. profile distinct mesenchymal cell populations in mouse adipose during embryonic development and obesity, identifying a new role for transcription factor BCL11b in dermal adipocyte differentiation. Learn more here: ➡️ tinyurl.com/gd351907
In this study, Kochman et al. identifies RPA2 variants as a genetic cause of telomere biology disorders, supporting a role for the RPA complex in regulating telomere length and stability. Learn more here: ➡️ tinyurl.com/gd352032
In this Outlook, Wang et al. discuss a new G&D study by Chen et al. that describes how the SAGA complex cooperates with transcription factors like MYC and MAF to drive oncogenic programs in multiple myeloma. Read the Outlook: ➡️ tinyurl.com/gd352186
In this study, Chen et al. show that ADA2B of the SAGA transcription coactivator complex regulates key oncogenic programs (like those driven by MAF, MYC, E2F, and mTORC1) in multiple myeloma, revealing a novel therapeutic vulnerability. Learn more here: ➡️ tinyurl.com/gd351789
In this Outlook, Renaud discusses a new G&D study by Esbin et. al, and highlights the mechanisms involved in syncytiotrophoblast fusion, commenting on TFEB-dependent and TFEB-independent processes. Read the Outlook: ➡️ tinyurl.com/gd352198
In this Outlook, Renaud discusses the mechanisms involved in syncytiotrophoblast fusion and comments on TFEB-dependent and TFEB-independent processes. Read the Outlook: tinyurl.com/gd352198
In this study, Esbin et al. report a critical new role for the transcription factor TFEB in controlling fusogen expression and syncytiotrophoblast fusion during placental development. Learn more here: ➡️ tinyurl.com/gd351633
In this review, Bubenik et al. discuss the current advances in RNA therapeutics and RNA targeted therapies that are gaining traction in the treatment of neurological and neuromuscular diseases. Learn more here: ➡️ tinyurl.com/gd351612
