The multiple roles of Salt-Inducible Kinases in regulating physiology Wonder kinase family SIK1/2/3 senses circadian cues, nutrients & inflammation "Sleepy"🐭◀️gain-of-function variants (free of PKA phospho & 14-3-3 binding) of Sik1, 2 or 3 #PhysiolRevjournals.physiology.org/doi/full/10....