Ok, let's try a #ResearchIntegrity#StarterPackgo.bsky.app/5NJ9Z4N
Ah this is great! There's an open science one somewhere too and I'm thinking of making a preprint focussed one.
Excellent guide! There's now a #preprints#SciencePublishing
We need more field-specific solutions and those with a background in those fields as the drivers of change (8/8)We need more field-specific solutions and those with a background in those fields as the drivers of change (8/8)
Just an out-loud thought. My main point is that there is not a single approach that applies across fields but there's a pretence that this is the only way forward. (7/8)Just an out-loud thought. My main point is that there is not a single approach that applies across fields but there's a pretence that this is the only way forward. (7/8)
In biology we shouldn't be aiming to reproduce exact experiments but to find the same conclusions and observations with different approaches - that's how you can be confident in a finding. (6/8) In biology we shouldn't be aiming to reproduce exact experiments but to find the same conclusions and observations with different approaches - that's how you can be confident in a finding. (6/8)
But not being able to reproduce individual experiments is not inherently a surprise or a bad sign - there are too many variables. (5/8) But not being able to reproduce individual experiments is not inherently a surprise or a bad sign - there are too many variables. (5/8)
Now if an entire paper (or more importantly it's conclusions) can't be reproduced then yes that is a problem. If details to replicate experiments are not provided then that too is a problem. If data or materials are not shared, that is a problem. (4/8)Now if an entire paper (or more importantly it's conclusions) can't be reproduced then yes that is a problem. If details to replicate experiments are not provided then that too is a problem. If data or materials are not shared, that is a problem. (4/8)
For example, cell culture density can have huge effects on signalling pathways and yet it's not something that is monitored as closely or reproducibly as it should be. Room temperature can also have a big effect (or how quickly you work) yet how many are recording this daily? (3/8)For example, cell culture density can have huge effects on signalling pathways and yet it's not something that is monitored as closely or reproducibly as it should be. Room temperature can also have a big effect (or how quickly you work) yet how many are recording this daily? (3/8)