BLUE
JA
James Antony
@jameswardantony.bsky.social
asst prof of cog neuro at cal poly | dad | formerly uc davis, princeton, northwestern, lawrence | graying child | he/him | blm | dm for papers
230 followers295 following20 posts

Drift in this scenario (left) ⬆️ memory most at long RIs (middle), including w/ fully scrambled temporal contexts (final data point). Thus, drift ⬆️ memory even w/o contextual support. As predicted, drift ⬆️ error between model predictions and outcomes, as shown in hippocampal area CA3 (right). 14/

Left: Depiction of modeling paradigm for cases with and without drift.
Middle: Drift improved memory performance, especially at long RIs and with a fully scrambled temporal context.
Right: Error in hippocampus area CA3 in the model was greater in the drift than no drift condition.
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We found temporal abstraction by training the model w/ a range of ISIs (increasing powers of 2). Increasing ISIs resulted in greater strengthening in slower-drifting pools from EC-CA3. This helps retain memory access for longer according to the temporal regularity of training. 15/

Left: Depiction of weights between the entorhinal cortex and area CA3 in various temporal context pools. Right: Greater weight strengthening occurred in slower drifting pools with increasing ISIs.
1
JA
James Antony
@jameswardantony.bsky.social
asst prof of cog neuro at cal poly | dad | formerly uc davis, princeton, northwestern, lawrence | graying child | he/him | blm | dm for papers
230 followers295 following20 posts