In new study led by Frances Welsh, we map how mutations to influenza affect neutralization by antibodies from humans of various ages   We find differences in mutation effects among age groups   Virus seems to evolve especially to escape antibodies of teenagers   www.biorxiv.org/content/10.1...

Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

As background, human influenza constantly evolving. So people exposed to different strains, depending on their age & idiosyncratic history of infection/vaccination.   Different exposure histories cause people to make antibodies w different specificities   rupress.org/jem/article/...

Very cool