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Bloom lab
@jbloomlab.bsky.social
Lab studying molecular evolution of proteins and viruses. Affiliated with Fred Hutch & HHMI. jbloomlab.org/
2.2k followers356 following188 posts
BLjbloomlab.bsky.social

Here are the locations of the mutations on the HA structure. Two are on the head, one is in the stalk. (Go to this link dms-viz.github.io/v0/?data=htt... to look at structure interactively)

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BLjbloomlab.bsky.social

The California human cases *lack* the A160T (a la A156T or A172T) mutation that was present in a recent human case from Missouri and is known to cause a substantial antigenic change. bsky.app/profile/jblo...

BLjbloomlab.bsky.social

Here is analysis of HA mutations in H5 influenza case in Missouri resident without known contact w animals or raw milk. TLDR: there is one HA mutation that strongly affects antigenicity, and another that merits some further study.

1
BL
Bloom lab
@jbloomlab.bsky.social
Lab studying molecular evolution of proteins and viruses. Affiliated with Fred Hutch & HHMI. jbloomlab.org/
2.2k followers356 following188 posts
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