Can we predict AMR evolution?? We sure can try! New study published today in PNAS www.pnas.org/doi/10.1073/...
New call for postdoc fellowships from the 🇪🇸 govt. My brilliant colleague Cristina Vieitez and I are happy to jointly sponsor candidates who'd like to join us in beautiful Salamanca & develop methods for characterizing and optimizing microbial consortia. More info ⬇️. www.aei.gob.es/convocatoria....
🔥 Just under 1 month until the MEEhubs 2024 conference! 🔥 Detailed program now online on our website - Submission deadline for virtual posters TODAY!! - Registration deadline in-person hubs TODAY!! (Oxford closed) - Registration for virtual-only attendance til Jan 5 2024! #MicroSkywww.meehubs.org
This is a super cool piece of work - Olivia Kosterlitz & Benjamin Kerr et al Evolutionary “Crowdsourcing”: Alignment of Fitness Landscapes Allows for Cross-species Adaptation of a Horizontally Transferred Gene academic.oup.com/mbe/article/...#MicroSky#EvoSky
Abstract. Genes that undergo horizontal gene transfer (HGT) evolve in different genomic backgrounds. Despite the ubiquity of cross-species HGT, the effects of s
Thank you, Patricia!
🚨 Preprint alert 🚨 β-lactamase production in enterobacteria induces collateral sensitivity to other antibiotics! We believe that these findings expose the Achilles’ heel of β-lactamase producing bacteria! With @sanmillan.bsky.social#MicroSky
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Applications open for my fully funded PhD studentship "CDTS315: Pollution from source to cetaceans – antimicrobials as a case study for One Health wastewater pollution" hosted by Bangor University @NatResWales www.plymouth.ac.uk/study/resear...
New preprint! We conjugated a panel of MDR plasmids into E. coli and found parallelisms in the differential expression of metabolic genes. @alanmcn1.bsky.social@brockhurstlab.bsky.socialwww.biorxiv.org/content/10.1...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
New preprint on the evolution of natural transformation. We measured transformation rates in 100s of #Acinetobacter#Legionella pneumophila. Key arising question: why are so many strains non-transformable if the many recent transitions to non-transformability seem deleterious? 1/4
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
1st post on a ms just out in #MBE. We have been playing with the idea that horizontal gene transfer by shaping genetic backgrounds can affect patterns of adaptation by point mutations (or other changes) in core genes. We apply a recent method to identify significant chronologies HGT -> mutation. 1/3