Thanks as always to my co-authors, and you for reading this! 4/4
Ultimately, we hope that by clarifying the specific roles of various brain regions in tinnitus, we can start to work towards considering novel treatment approaches that might better account for differences in symptoms and treatment response across individuals. 3/4
The idea is to re-focus the specific role of this brain structure in tinnitus. In most other literature outside of tinnitus, the hippocampus being involved in maintaining memories is pretty uncontroversial, while in tinnitus it's most often referred to in an "emotional" role. 2/4
I will do - he was speaking highly of you the other day, in fact!
Thanks as always to my co-authors, Sukhbinder Kunar, Paris Ash, Ester Benzaquén and Phil Gander, as well as everyone who took part in the large online misophonia study. And you, for getting to the end of this thread! (6/6)
Ultimately, all of this works towards reframing misophonia in a way that we can properly understand the mechanisms behind the disorder and lead towards developing effective treatments for individuals with misophonia. (5/6)
In the second paper, Sukhbinder, Phil & I frame misophonia within a social cognitive framework, highlighting that a sound-based model of misophonia misses key components, such as importance of social context, involvement of motor cortex & insula, and high mimicry prevalence. (4/6)
Mimicry is elicited most frequently during orofacial trigger sounds and can often provide some degree of relief. These results and previous imaging literature highlight the importance of the perception of the actions of others in triggering misophonia. Hence the next paper... (3/6)
The first paper was based on hypotheses created by some of Sukhbinder's and others' earlier fMRI findings, which implicated the motor cortex in misophonia, as well as anecdotal and small case reports. In a large cohort, we find a high prevalence of mimicry in misophonia (2/6)
ReadCube link here: rdcu.be/dokvD