Excited to share my 1st paper with @bridgetwatson.bsky.social@taylorlabgroup.bsky.socialacademic.oup.com/ismej/articl... where we ask “when would using a defence system (CRISPR-Cas) be selectively advantageous over mutations that block phage binding?”1/10

Conditions for the spread of CRISPR-Cas immune systems into bacterial populations

Abstract. Bacteria contain a wide variety of innate and adaptive immune systems which provide protection to the host against invading genetic material, inc

David & Sylvain built a deterministic mathematical model & found that when 2 populations of bacteria, one with, one without a CRISPR-Cas system meet, the difference in the frequencies of cells with phage defences in each population determines which population is selected for 2/10

Congrats! This is so cool 😍