BLUE
Profile banner
JT
Josh Trebach, MD
@jtrebach.bsky.social
ER doc. Toxicologist. I tweet about poisons & cats. Tweets/opinions/DMs = my own (not employer’s) & not medical advice. 🏳️‍🌈 contact = ToxTrebach@gmail.com
2.5k followers26 following58 posts
JTjtrebach.bsky.social

SMFA is a white powder that looks like flour or sugar. When ingested, SMFA gets converted into monofluoroacetyl-CoA (MFA-CoA). This looks a lot like acetyl-CoA, an important compound in the Krebs cycle.

1

JTjtrebach.bsky.social

Your mitochondrial enzymes are very stupid (sorry) and they can’t tell the difference between your name brand acetyl-CoA and the fugly knock off brand MFA-CoA…. So MFA-CoA gets introduced into the krebs cycle…and the end result is that the whole cycle STOPS and shuts down

1
Profile banner
JT
Josh Trebach, MD
@jtrebach.bsky.social
ER doc. Toxicologist. I tweet about poisons & cats. Tweets/opinions/DMs = my own (not employer’s) & not medical advice. 🏳️‍🌈 contact = ToxTrebach@gmail.com
2.5k followers26 following58 posts