New paper day! "Multiband acquisition sequences for fMRI: Proceed with caution" apertureneuro.org/article/9129...@layerfmri.bsky.social@fmri-today.bsky.social#neuroskyence

Couldn't agree more. Side-note: I'm a big fan of multi-echo, but the sequences I've been dealing with are quite slow (~3.5s) and ideally I'd like something a little faster. Do you have any experience with multiband multi-echo? Might it dampen some of MBs detriments?

Everyone loves multiband/SMS sequences for fMRI right? It let's you go faster, get higher-resolution voxels, all that good stuff. I mean, the HCP used MB=8... Must be OK to do that for your 25-subject study too, right? Counterpoint - No! Stop it.

Always good to do some tSNR piloting with sequence parameters...

That’s awesome!

This is great Matt and I agree with the sentiment of applying MB judiciously. One thing that I've noticed in discussions is that some centers allow their PIs little room to tailor params. Hopefully they can use this as backup if they want something other than HCP params!

Your caution is warranted but I will argue using HCP seqs are still great for small N studies. We used them for a study with n=37. Fantastic, highly robust and high-resolution results (when analysed properly). The results didn't change much after n=10. doi.org/10.1093/cerc...doi.org/10.1101/2022...

SMS can be very useful for clinical diffusion MRI in neuroradiology, but we were initially suprised by this artifact: doi.org/10.1161/STRO... Fortunately, we knew the discussion about slice leakage from the fMRI literature 🧠📈