New preprint with @mcagiada.bsky.social@sokrypton.orgdoi.org/10.1101/2024...

I'm excited to present Francesco Pesce's work on developing, applying & experimental testing of a method to design intrinsically disordered proteins. Our algorithm combines MC sampling in sequence space with an efficient CG simulation model and alchemical free-energy calculations. 🍝 🧶🧬