Y? (Sorry, couldn’t resist the pun)
My son's high school IB Biology class is learning protein tertiary and quaternary structure so Monday I gave a lecture about septin complexes and guanidine rescue of Arg-mutant proteins. Class sent me a thank-you card, includes: "it made me want to pursue a research career even more". So fulfilling❤️
Crystallographers, please help me understand: The top image shows data from a protein that the authors interpreted as binding to GTP. The bottom image shows data from the same protein in another crystal. Those authors concluded that the bound nucleotide is GDP. 🤷🏽♂️
Just read about an S. cerevisiae strain made by linearizing and integrating a pRS426-based plasmid, which encodes components of the 2-micron plasmid. It hadn't occurred to me that this would be tolerated (since integrating ARS/CEN→☠️). Anybody have reference for use of this approach?
Our first entirely “dry lab” paper! We explored what happens during evolution when a septin protein loses GTPase activity or GTP/GDP binding altogether. Since septins oligomerize across the nucleotide-binding pocket, the interface adapts! This has happened a lot www.frontiersin.org/articles/10....
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into ...
🎺 We are hiring! Join our department of Biology at UMass Boston as a tenure-track Assistant Professor (Biochemistry). "Biochemistry" is understood broadly. Spread the word. employmentopportunities.umb.edu/boston/en-us...
Hi! I’m Amanda Moehring, looking to recruit a PhD student to work on an awesome project on the genetic snd neural basis of female aggression, in Drosophila (flies). (Psst, I’m also in Canada, where we have nationalized healthcare, bodily autonomy for women, and gun control).