I ❤️❤️ expansion microscopy- great to see it used on microbes!🦠 🧫
Really beautiful piece of work from Nadine Ziemert et al - Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides www.nature.com/articles/s41...#MicroSky#EvoSky
Glycopeptide antibiotics (GPAs) are microbial natural products synthesized by multiple enzymes, including a nonribosomal peptide synthetase for assembly of the peptide core. Here, the authors use comp...
This is really cool - using the distribution of cells in a pipette tip for CFU quantification: www.nature.com/articles/s41...
Using agar media suspended in pipette tips and a standard camera, the geometric viability assay provides a user-friendly and scalable update to standard colony-forming-unit-count approaches.
How many bacterial pathogens infect humans? by Roberto In casual conversations I used to say that the number of bacteria causing human disease was small, a few dozen, perhaps around 100. Was I wrong! A paper by Bartlett et al. (2022) puts the number at... Read more > tinyurl.com/kmhuhh94#MicroSky
Thank you so much! I’m very honoured and really enjoyed the APC Microbiome symposium - so many awesome students and post docs doing great stuff! 🦠🧫
I am looking for a graduate student and a postdoc to join my group! We are a computational group working on understanding evolution in natural populations with a large emphasis on the microbiome. Please get in touch by dm or email! garud.eeb.ucla.edu
Those guys indeed! Yes happy to do some PR on behalf of these cuties
Authors recommend replication - a key aspect science. And I was happy to see Christensenellaceae mentioned b/c their heritability has been replicated, and of course they are really cool. 🦠🧫
There are limitations but this is a neat tool to play around with www.nature.com/articles/s41...bugsigdb.org (I wish we had something like this for mechanistic microbiome studies)
A database of microbial signatures is used for systematic comparison of differential abundance patterns.