"In all of Octavia Butler's work, she depicts the protagonist, usually a black woman, with physical or mental disability, or with chronic illness. Scholarship has been slow to discuss her work in terms that give full voice to the intersection of race, gender, and disability." - THERÍ A. PICKENS 1/

Octavia Butler and the Aesthetics of the Novel on JSTOR

THERÍ A. PICKENS, Octavia Butler and the Aesthetics of the Novel, Hypatia, Vol. 30, No. 1, SPECIAL ISSUE: New Conversations in Feminist Disability Studies (WINTER 2015), pp. 167-180

I’ve been reading Wild Seed and also noting that the lead characters are all trans / gender fluid

"Speech Sounds" comes to mind as a story where everyone is disabled.