Today in Cell, we report our evidence for a covalent linkage between small RNAs and N-glycans via acp3U. Made possible due to the dedicated work of co-first authors Axe Xie and Peiyuan Chai and collaboration with Ben Garcia's lab at WashU. www.cell.com/cell/abstrac...

Super cool work

Combining careful new MS instrumentation with classical glycobiology tools (e.g. PNGaseF) and critical organic synthesis intuition and help from Carolyn Bertozzi and postdoc Nick Till enabled rigorous evaluation of the nature of the RNA-glycan linker.