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Joe Dillard
@sacculus.bsky.social
Bacteriologist. We study Nesseria, Gardnerella, and all things related to peptidoglycan. Professor at UW-Madison.
103 followers152 following14 posts
JDsacculus.bsky.social

🧪 We've published our first paper on Gardnerella. There is extensive phase variation in all the Gardnerella species we examined. It effects surface proteins, toxin production, and human cervix infection ex vivo. doi.org/10.1128/msph...

Colonies of the bacteria Gardnerella, strain 3336, grow on an agar plate and appear as large or small colonies (left panel). The number of Gardnerella surviving in an infection of huaman cervix tissue in the lab is depicted in a bar graph, and the number of small colony variants that survive is greater than those of the large colony variants (right panel).
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JDsacculus.bsky.social

The phase variation work was a collaboration with Kim Jefferson's lab at VCU and Caitlin Pepperell's lab @csp.bsky.social here at UW. Erin Garcia in the Jefferson lab and Amy Klimowicz in my lab discovered the phase varriation at the same time, and we decided to work and publish together.

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JD
Joe Dillard
@sacculus.bsky.social
Bacteriologist. We study Nesseria, Gardnerella, and all things related to peptidoglycan. Professor at UW-Madison.
103 followers152 following14 posts