So, let’s assume there’s conflict, but we’ve largely missed it. How can we discover antagonistic interactions between archaea and bacteria? Experiments are good, of course – chuck them together into the Thunderdome, maybe take away their food, and see if somebody turns nasty.4/10

But we thought a computational approach might also be informative. So we started looking, in archaeal genomes, for proteins that looked like they might do some damage to bacteria, and specifically bacteria. 5/10