Sharing our latest paper as my first post here 🔵 💙 Plasmids encode Type IV CRISPR-Cas to fight other plasmids💥⚔️ Now out in Cell Host & Microbe www.sciencedirect.com/science/arti...

Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans

Plasmid-encoded type IV-A CRISPR-Cas systems lack an acquisition module, feature a DinG helicase instead of a nuclease, and form ribonucleoprotein com…

Our new paper on siderophore gene expression heterogeneity across space and time in #Pseudomonas#CellReportswww.cell.com/cell-reports...

Space and genealogy determine inter-individual differences in siderophore gene expression in bacterial colonies

Mridha et al. show that the spatial positioning of cells within colonies and genealogical effects drive cellular siderophore gene expression heterogeneity in Pseudomonas aeruginosa bacteria. Functiona...

New preprint from my postdoc with Bonnie Bassler! We show that phage VP882 responds to different host factors depending on the environmental context of the infected host, highlighting the need to study phage-bacteria interactions in relevant contexts to get the full picture. #MicroSky 🦠

Check out this latest work by @catarmbruster.bsky.socialjournals.asm.org/doi/10.1128/...

Persistence and evolution of Pseudomonas aeruginosa following initiation of highly effective modulator therapy in cystic fibrosis | mBio

The highly effective cystic fibrosis transmembrane conductance regulator modulator therapy Elexakaftor/Tezacaftor/Ivacaftor (ETI) has changed cystic fibrosis (CF) disease for many people with cystic f...

Very excited to announce our transdisciplinary AMR workshop 🎉 Join us to hear perspectives and discussion from patient activists, journalists, philosophers, microbiologists, historians, clinicians, policy makers, and artists. More info: www.torch.ox.ac.uk/event/commun...

Inspiring & thought-provoking talk @cbi by Roshni Mooneeram Do we have an inclusive culture in research that allow women to thrive? When #feminism & ethics are not convincing enough, be pragmatic; diverse teams are better at decision making, offer a wider pool of possible solutions to pick from

For many years, we have worked on cooperative aspects of siderophore sharing. Here, we show that siderophores from environmental pseudomonads can have strong competitive and antibacterial effects against pathogens through the induction of iron starvation. elifesciences.org/reviewed-pre...

This is a very nice study that showcases the role of siderophores as potential antimicrobials.

Workshop‼️ One Health and antimicrobial resistance: role of antibiotics, antimicrobial peptides and biocides   29 & 30 January 2024 in Berlin, Germany and online

Together with @frimanscience.bsky.socialwww.biorxiv.org/content/10.1...www.biorxiv.org/content/10.1... from sequence data!