They tried anti-IL13 for human pulmonary fibrosis, it had no effect. Might have been compensated for by IL4 or other mechanisms. We only found IL10/TGFbeta in our (sadly long gone) mouse model.

Yeah, that's exactly why I dove in there based on your comment. I hypothesize that the roles of IL4/IL13 vs IL10/TGFbeta don't overlap as much as we were taught in the past, so always looking for more evidence....

Would like to retire • Jackson #IL01#IL13#IL17

My rep is a bootlicker #IL13

JCjonathancohn.bsky.socialJun 17, 2024 2:32am

24 House Democrats joined the GOP to vote for an amendment to block Biden's executive order limiting the transfer of military equipment to local police departments.

Illinois bad Dems Jackson #IL01#IL05#IL08#IL10#IL13#IL17

JCjonathancohn.bsky.socialMay 23, 2024 2:26am

71 Democrats just joined almost every Republican in a bill to undermine cryptocurrency regulations. clerk.house.gov/evs/2024/rol...

St. Louis-area Representatives: YES: Budzinski (D-IL13), Bost (R-IL12), Miller (R-IL15), Wagner (R-MO02), Luetkemeyer (R-MO03), Smith (R-MO08) NO: Bush (D-MO01) #TikTokBan#KeepTikTokclerk.house.gov/evs/2024/rol...www.huffpost.com/entry/tiktok...

House Passes Bill That Could Block TikTok In The U.S.

ByteDance, TikTok's parent company, was given six months to sell the video app or face a ban, but the proposal faces bipartisan opposition in the Senate.

@rahaeli.bsky.social My spouse has eczema & is going to go on Dupixent; he's telling me stuff about how it "is a replacement for interlukin 4 and binds to IL13 receptor" & down-regulates immune system response & key ones he thinks are mast cells, reducing their desire to trigger. Is this new data?