Great talk by Tamir Gonen at #GDChBioChem2024@gdchbiochem.bsky.socialwww.sciencedirect.com/science/arti...
MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function | bioRxiv https://www.biorxiv.org/content/10.1101/2024.09.18.613782v1?rss=1
MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function www.biorxiv.org/content/10.1101/2024.09.18.613782v1
The detailed understanding of fluticasone, a widely prescribed medicine for allergic rhinitis, asthm
A MicroED structure of the MAL TIR-mediated MyD88 TIR higher-order assembly reveals a two-stranded arrangement of TIR domains similar to MAL TIR self-assemblies #MicroED#MyD88#TIRDomaint.co/K0Jt3tVITD
Energy filtering enables macromolecular MicroED data at sub-atomic resolution www.biorxiv.org/content/10.1101/2024.08.29.610380v1
High resolution information is important for accurate structure modelling. However, this level of de
Energy filtering enables macromolecular MicroED data at sub-atomic resolution www.biorxiv.org/content/10.1101/2024.08.29.610380v1
High resolution information is important for accurate structure modelling. However, this level of de
Kumar et al.: TAAM refinement on high-resolution experimental and simulated 3D ED/MicroED data for organic molecules #DED #ElectronDiffraction #MicroED #IUCr https://journals.iucr.org/paper?S2053229624005357
With the currently avalaible 3D ED data it is possible to observe details of electrostatic potential deformations due to chemical bonding in organic crystals. The deformation signal is strong enough to see the benefits of using a more accurate potential model (TAAM) in achieving a better fit of the model to the experimental data.
Mauro Gemmi: 3D ED/MicroED entering a new era ... #IUCr https://journals.iucr.org/paper?S205322962400490X
Aragon et al. [Acta Cryst. (2024), C80, ???–???], by reporting the discussion and the final conclusions of a round table held during a symposium at the National Center for CryoEM Access and Training, well describe all the advances that have been made for the application of 3D ED/MicroED to pharmaceutical and macromolecular nanocrystals and propose possible future scenarios.
Using both X-ray and microED data, the structure of the main fragment of a protein of unkown function was solved using a predicted model of that domain as a starting point #ElectronDiffraction#ProteinStructurePrediction#BacterialProteinst.co/Wl23bjJbXp
