A genetic framework for RNAi inheritance in Caenorhabditis elegans www.biorxiv.org/content/10.1101/2024.10.02.616260v1

A genetic framework for RNAi inheritance in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2024.10.02.616260v1

Gene regulation by RNA interference (RNAi) is a conserved process driven by double-stranded RNA (dsR

Karma hiperlipidemi (kandaki yağ (lipid) seviyelerinin normalden yüksek olması) için yeni RNAi terapötiği Zodasiran, 24 hafta sonra trigliseritlerde önemli düşüşler bildirildi. Faz 2b www.nejm.org/doi/full/10....

Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia | NEJM

Angiopoietin-like 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases and hepatic uptake of triglyceride-rich lipoprotein remnants. ANGPTL3 loss-of-function carriers have lower levels of trigl...

If you happen to be in Zurich in two weeks, drop by the ETH to discuss our latest findings in the evolutionay fine tuning of plant antiviral immunity and cell type specialization of RNAi-based defenses!

Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans www.biorxiv.org/content/10.1101/2024.09.24.614643v1

Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2024.09.24.614643v1

RNA interference (RNAi) is widely used in life science research and is critical for diverse biologic

Structure - silencing duration relationships in RNAi medicines in rapidly dividing cells www.biorxiv.org/content/10.1101/2024.09.09.612002v1

Structure - silencing duration relationships in RNAi medicines in rapidly dividing cells https://www.biorxiv.org/content/10.1101/2024.09.09.612002v1

RNA interference (RNAi)-based medicines offer precise targeting of virtually any transcript, making

Does mammalian #Dicer#RNAionlinelibrary.wiley.com/doi/10.1002/...

Você já imaginou ter o poder de controlar a atividade dos genes? Bem, é aí que entra o RNAi, um mecanismo intrigante e versátil encontrado em nosso corpo. manfrinemelo.com/rnai-o-que-e...

RNAi: O que é Ácido Ribonucleico Interferente?

Você já imaginou ter o poder de controlar a atividade dos genes? Bem, é aí que entra o RNAi, um mecanismo intrigante e versátil encontrado em nosso corpo.

🚨Mosquito/fly tweeps🚨 Does anyone know of an alternative to E-RNAi? I/we have used that platform to design dsRNAs for more than 15 years and it appears as though the URL is no longer available. Any help would be much appreciated! TIA!

a man is crying while laying on a couch and saying i 'm begging .

ALT: a man is crying while laying on a couch and saying i 'm begging .

Next, we compared gene expression across lichen thallus parts / developmental stages. Surprisingly, many F-box proteins and genes related to RNAi were upregulated in apothecia, the fruiting bodies; secreted proteins were often upregulated in the growing edge 3/7

#MedSky🧪#IDSky#SARSCoV2#RNAi#COVIDwww.nature.com/articles/s41...

SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia - Nature Communications

Here, the authors provide evidence that SARS-CoV-2 N protein leads to autophagic degradation of Dicer, XPO5, SRSF3, and hnRNPA3, inducing DNA damage and proteotoxic stress, eventually causing pneumoni...