I've traveled down a rabbit hole. Fun fact, melanoma is one of the cancers most likely to metastasize to the brain. But that is not the rabbit hole. The rabbit hole is amyloids. (The first rabbit hole was the similarity of skin and brain cells) www.cancer.gov/news-events/...
Melanoma cells that travel to the brain produce their own amyloid beta, helping the cancer cells survive and form metastases, a new study in mice shows.
Similarly, but also the opposite, I was watching the local news at my parents' house & an ad came on for "Amyloid.com" & I thought, "Don't they no longer think amyloids cause Alzheimer's?" And the site seems to be trying to sell you amyloid meds but doesn't mention Alzheimer's? Just "memory."
Six for six, and I don't particularly keep up with science like I used to, except for the amyloids that are colonizing my brain.
Quiz time! Just for fun, it doesn't count toward your grade. Test your science knowledge and maybe learn some things (or take pride that you already did) www.scientificamerican.com/game/science... 🧪 by @parshallison.bsky.social
Put your science knowledge to the test with this week’s news quiz. Play now.
🤯 Amyloids (proteins!) that are inherited from parent to offspring and directly influence trait expression. The epigenetic toolkit grows! 🧪 "Noncanonical inheritance of phenotypic information by protein amyloids" by Eroglu et al. (2024, Nature Cell Biology) www.nature.com/articles/s41...
Eroglu et al. describe protein amyloid structures that are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. MSTR protein loss results in a transgenerationa...
Amyloids: love them or hate them, you can't ignore them. "We propose that this epigenetic information is transmitted by amyloid-like structures that are inherited through the germline and segregate to both somatic and germ lineages of WT C. elegans offspring..." www.nature.com/articles/s41...
Eroglu et al. describe protein amyloid structures that are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. MSTR protein loss results in a transgenerationa...
Non-standard proteins in the lenses of AlphaFold3 - case study of amyloids www.biorxiv.org/content/10.1101/2024.07.09.602655v1
Motivation: The recent release of AlphaFold3 raises a question about its powers and limitations. Her
Non-standard proteins in the lenses of AlphaFold3 - case study of amyloids www.biorxiv.org/content/10.1101/2024.07.09.602655v1
Motivation: The recent release of AlphaFold3 raises a question about its powers and limitations. Her
Strategies to Combat COVID-19-Linked Brain Amyloids and Dementia/Alzheimer www.thailandmedical.news/news/strateg...
