I just heard that Alexander Tomasz died on Monday. I didn't know him, but I met him once while I was a graduate student working on pneumococci. He did pioneering work on pneumococcal competence, discovering competence factor. His work on autolysins and penicillin binding proteins was tremendous.
2) Pneumococcal vaccines. Pneumococci are bacteria which are *one* of the causes of clinical diagnosis called "pneumonia". Pneumococcal vax protect us against *this* cause of pneumonia, but not others (including viruses). Prevnar-20 pneumococcal vax is a one done vax: good for life. CDC info here:
Armin Braun already speculated in 1947 that DNA may be involved in this transformation process. But research really took off in 1967, when Rob Schilperoort showed that Agrobacterium RNA could hybridize with crown gall DNA,indicating that bacterial DNA had indeed been transferred.
Molecular and Structural Basis of Oligopeptide Recognition and Transport by the Ami Transporter System in Pneumococci www.biorxiv.org/content/10.1101/2023.12.05.570199v1
ATP-binding cassette (ABC) transport systems are crucial for bacteria to ensure sufficient uptake of
Molecular and Structural Basis of Oligopeptide Recognition and Transport by the Ami Transporter System in Pneumococci www.biorxiv.org/content/10.1101/2023.12.05.570199v1
ATP-binding cassette (ABC) transport systems are crucial for bacteria to ensure sufficient uptake of
Oxidation of hemoglobin in the lung parenchyma facilitates the differentiation of pneumococci into encapsulated bacteria www.biorxiv.org/content/10.1101/2023.11.14.567109v1
Pneumococcal pneumonia causes cytotoxicity in the lung parenchyma but the underlying mechanism invol
Oxidation of hemoglobin in the lung parenchyma facilitates the differentiation of pneumococci into encapsulated bacteria www.biorxiv.org/content/10.1101/2023.11.14.567109v1
Pneumococcal pneumonia causes cytotoxicity in the lung parenchyma but the underlying mechanism invol